cpsf6 protein Search Results


cpsf6  (Proteintech)
93
Proteintech cpsf6
SNW1 interacts with <t>NUDT21/CPSF6</t> to regulate SRPK1 splicing (A) Proteins interacting with SNW1 were immunoprecipitated with anti-SNW1 antibody and identified by LC‒MS/MS. Table lists the top 10 SNW1-associated proteins in T24 cells. (B) Pearson correlation analysis showing associations between SNW1 and NUDT21, and SNW1 and CPSF6, in the TCGA cohort. (C and D) CoIP validation of interactions between endogenous SNW1, NUDT21, and CPSF6. (E and F) Western blot analysis of SRPK1 protein following NUDT21 (E) or CPSF6 (F) knockdown. (G–J) RT-qPCR analysis of SRPK1-L (G, I) and SRPK1-S (H, J) transcript levels. Data are presented as mean ± SD, ∗∗ p < 0.01, ∗∗∗ p < 0.001 (one-way ANOVA). (K–N) Transwell assays show reduced migration and invasion of T24 (K, L) and UM-UC-3 (M, N) cells after NUDT21 or CPSF6 knockdown. (O and P) RIP assays with anti-NUDT21 (O) or anti-CPSF6 (P) antibodies showing reduced SRPK1 pre-mRNA enrichment in SNW1 KD cells relative to Control KD cells. Data are presented as mean ± SD, ∗∗∗ p < 0.001 (one-way ANOVA).
Cpsf6, supplied by Proteintech, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 93 stars, based on 1 article reviews
cpsf6 - by Bioz Stars, 2026-04
93/100 stars
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recombinant human cpsf6 protein myc ddk tagged  (Creative BioMart)
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Recombinant Human CPSF6 fused with MYC DDK tag at C terminal was expressed in HEK293 The protein encoded by this gene is one subunit of a cleavage factor required for 3 RNA cleavage and polyadenylation
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recombinant human cpsf6 gst (n-term) protein  (Novus Biologicals)
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Recombinant Human CPSF6 GST (N-Term) Protein
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recombinant mouse cpsf6 protein  (Creative BioMart)
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Recombinant Mouse CPSF6 full length or partial length protein was expressed http www creativebiomart net Recombinant Mouse CPSF6 Protein 440415 htm
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recombinant human cpsf6 protein  (Novus Biologicals)
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The Recombinant Human CPSF6 Protein has been validated for the following applications Western Blot ELISA Protein Array Immunoaffinity Purification
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cpsf6 recombinant protein antigen  (Novus Biologicals)
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CPSF6 Recombinant Protein Antigen
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cpsf6 nm 001013391 mouse recombinant protein  (OriGene)
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Purified recombinant protein of Mouse cleavage and polyadenylation specific factor 6 Cpsf6 with C terminal MYC DDK tag expressed in HEK293T cells 20ug
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cpsf6 nm 007007 human recombinant protein  (OriGene)
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Recombinant protein of human cleavage and polyadenylation specific factor 6 68kDa CPSF6
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recombinant human cpsf6 protein gst tagged  (Creative BioMart)
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Recombinant Human CPSF6 1 a a 478 a a fused with GST tag at N terminal was expressed in Wheat Germ The protein encoded by this gene is one subunit of a cleavage factor required
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SNW1 interacts with NUDT21/CPSF6 to regulate SRPK1 splicing (A) Proteins interacting with SNW1 were immunoprecipitated with anti-SNW1 antibody and identified by LC‒MS/MS. Table lists the top 10 SNW1-associated proteins in T24 cells. (B) Pearson correlation analysis showing associations between SNW1 and NUDT21, and SNW1 and CPSF6, in the TCGA cohort. (C and D) CoIP validation of interactions between endogenous SNW1, NUDT21, and CPSF6. (E and F) Western blot analysis of SRPK1 protein following NUDT21 (E) or CPSF6 (F) knockdown. (G–J) RT-qPCR analysis of SRPK1-L (G, I) and SRPK1-S (H, J) transcript levels. Data are presented as mean ± SD, ∗∗ p < 0.01, ∗∗∗ p < 0.001 (one-way ANOVA). (K–N) Transwell assays show reduced migration and invasion of T24 (K, L) and UM-UC-3 (M, N) cells after NUDT21 or CPSF6 knockdown. (O and P) RIP assays with anti-NUDT21 (O) or anti-CPSF6 (P) antibodies showing reduced SRPK1 pre-mRNA enrichment in SNW1 KD cells relative to Control KD cells. Data are presented as mean ± SD, ∗∗∗ p < 0.001 (one-way ANOVA).

Journal: iScience

Article Title: SNW1 promotes lymphatic metastasis in bladder cancer by modulating SRPK1 splicing

doi: 10.1016/j.isci.2026.114811

Figure Lengend Snippet: SNW1 interacts with NUDT21/CPSF6 to regulate SRPK1 splicing (A) Proteins interacting with SNW1 were immunoprecipitated with anti-SNW1 antibody and identified by LC‒MS/MS. Table lists the top 10 SNW1-associated proteins in T24 cells. (B) Pearson correlation analysis showing associations between SNW1 and NUDT21, and SNW1 and CPSF6, in the TCGA cohort. (C and D) CoIP validation of interactions between endogenous SNW1, NUDT21, and CPSF6. (E and F) Western blot analysis of SRPK1 protein following NUDT21 (E) or CPSF6 (F) knockdown. (G–J) RT-qPCR analysis of SRPK1-L (G, I) and SRPK1-S (H, J) transcript levels. Data are presented as mean ± SD, ∗∗ p < 0.01, ∗∗∗ p < 0.001 (one-way ANOVA). (K–N) Transwell assays show reduced migration and invasion of T24 (K, L) and UM-UC-3 (M, N) cells after NUDT21 or CPSF6 knockdown. (O and P) RIP assays with anti-NUDT21 (O) or anti-CPSF6 (P) antibodies showing reduced SRPK1 pre-mRNA enrichment in SNW1 KD cells relative to Control KD cells. Data are presented as mean ± SD, ∗∗∗ p < 0.001 (one-way ANOVA).

Article Snippet: CPSF6 , Proteintech , Cat# 15489-1-AP; RRID: AB_10694140.

Techniques: Immunoprecipitation, Biomarker Discovery, Western Blot, Knockdown, Quantitative RT-PCR, Migration, Control